Blobs
If the Blobs occur because the Hotend pauses while printing, consider upgrading your Main Board or turning off SD Card Power Loss Recovery.
Blobs can also be caused by:
Slow SD cards
If the USB cable connecting OctoPrint to the printer is too long
a too low Bridge Speed in Prusa Slicer
In Cura
Print Settings > Custom > Preference Settings> Mesh Fixes > Check Maximum Resolution.
In Prusa Sliver
Consider entering a negative number for Extra length on restart to help prevent Blobs.